Prof. Ouyang has a multidisciplinary background in pharmaceutics & computer modelling, with experience in academia and industry. He obtained his bachelor (2000) and master (2005) in pharmaceutics from Shenyang Pharmaceutical University, China. He completed his PhD in pharmacy at The University of Queensland, Australia, in 2010 and progressed directly to his faculty position (Lecturer in Pharmaceutics, PI) at Aston University (UK). From the end of 2014, he moved to the University of Macau.
Since 2011, he has pioneered the integration of multi-scale modeling and in silico screening techniques in the field of drug delivery – “computational pharmaceutics“. He has published 2 books, 5 book chapters and over 100 refereed SCI journal papers. He held over 10 approved patents, which had been used in medicinal products. He edited the first book (John Wiley & Sons Inc., 2015) in this research area. He serves as the associate editor of <Drug Delivery and Translational Research>; , the editorial board or scientific advisor of <Asian Journal of Pharmaceutical Sciences>;, <Pharmaceutical Research>, and <Journal of Pharmaceutical Sciences>;. He established the first global in silico formulation platform. He successfully trained 6 PhD and over 30 master students.
His research focused on computational pharmaceutics, including:
- In silico formulation screening: to develop novel algorithms for the prediction of pharmaceutical formulations;
- Multi-scale modeling in drug delivery: to integrate quantum mechanics (QM), molecular dynamics (MD) and physiologically based pharmacokinetic (PBPK) modeling into drug delivery systems;
- Pharmacoinformatics: big data analysis of pharmaceutical information from the literature, patent, clinical trial and marketed products.
Yunsen Zhang designed the basic framework and computing algorithms of FormulationMM, contributing to various computing modules within the molecular modeling platform. His work spans molecular parameter generation, cyclodextrin-drug complexes, solid dispersion, liposomes, micelles, self-assembled drug nanoparticles, and drug transmembrane delivery. His focus lies in creating efficient algorithms to accelerate the development drug delivery through molecular modeling.
Chenyu Lin designed the technical framework of the Formulation platform, developed the middleware between the user interface and the computational code and is responsible for maintaining the platform.
Zhongmin Zhao develops and maintains FormulationMM.
As one of the developers at Formulation Platform, Zheng Wu specializes in designing the foundational framework of the web pages and continuously optimizes the interactive logic to ensure a user-friendly experience.