Platform Update Log

Latest improvements and development updates of the FormulationMM platform.

2025-04-25

  • Update the algorithm in small molecule generation.
  • Now GAFF2 and RESP charge serve for small molecules (atom number is less than 175).
  • Now GAFF2 and AM1-BCC charge serve for bigger molecules (atom number is equal to or more than 175).

2025-04-18

  • Supported the protonated and deprotonated drug molecules in "Cyclodextrin" module.

2025-03-29

  • Added new "Drug Transmembrane" module to enhance transport prediction.
  • Optimized GPU-based simulation kernel for liposome self-assembly.

2025-03-18

  • Refined molecular parameter generation pipeline with RDKit and Open Babel support.

2025-02-05

  • New visualization features added to support micelle structure rendering.
  • Updated documentation and step-by-step tutorials in the Protocol section.

2025-01-15

  • Improved docking preprocessing to support flexible ligand replacement.
  • Enhanced solid dispersion module with polymer blend prediction models.

2024-12-01

  • Initial launch of FormulationMM platform with 5 core modules: Liposome, Micelle, Nanoparticle, Cyclodextrin, Solid Dispersion.
  • Database of excipients and formulation systems now accessible under the Database menu.

For historical versions and patch notes, contact: um.formulationmm@gmail.com