FormulationMM

Liposome

Generate the initial files for molecular dynamics simulation of liposome.

Liposome

Platform Manipulations

Model Generation is required and cannot be removed.

Generation Method

Choose the Type of Lipid

Loading lipids…

Drug Input

Note: You can calculate it based on the molar ratio or encapsulation ratio. For example, molar ratio: POPC:drug = 10:1 equals number ratio: POPC:drug = 2000:200. Often two turns help: first determine lipid numbers, then drug numbers.

Model Conditions

Modification

Note: Model generation ~1–2 minutes. Model simulation requires more than 1 hour (depends on radius).

MUST READ before process: Run several turns of model generation to obtain an ideal model. Do not run simulation/analysis until the model looks good. Contact: um.formulationmm@gmail.com